SECTION 1Identification
| Product identifier | Polyjuice Base |
| Other means of identification | Ammonium hydroxide, 25% NH₃; aqueous ammonia; ammonia water; aqua ammonia. Solution CAS No. 1336-21-6. Product code PB-394. |
| Recommended use | Industrial raw material for formulating cleaning and polishing products; pH adjustment. |
| Restrictions on use | Industrial use only. Not for consumer use. Do not mix with bleach, chlorine products or acids. |
| Supplier (U.S.) | Tyrell Chemical Distributors 2019 Nexus Way, Off-World Industrial Park Main office: (555) 555-0192 Regulatory contact: R. Graff, Product Safety |
| Emergency telephone | (555) 555-0189, 24 hours (Tyrell emergency line). In a medical emergency, call 911. |
SECTION 2Hazard identification
Classification (29 CFR 1910.1200(d))
- Acute toxicity, oral, Category 4
- Skin corrosion/irritation, Category 1B, with corrosivity to the respiratory tract (Appendix A, A.1.2.4.2, and the note to C.4.4 in Appendix C)
- Serious eye damage/eye irritation, Category 1
Label elements
Signal word: DANGER Hazard statements:
|   Corrosion | Exclamation mark |
| Precautionary statements: Prevention | Do not breathe mists or vapors. Use only outdoors or in a well-ventilated area. Wash hands and any exposed skin thoroughly after handling. Do not eat, drink or smoke when using this product. Wear protective gloves, protective clothing, eye protection and face protection. |
| Response | If swallowed: Rinse mouth. Do NOT induce vomiting. If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. Wash contaminated clothing before reuse. If inhaled: Remove person to fresh air and keep comfortable for breathing. If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a poison center or doctor. Specific treatment: see Section 4. |
| Storage | Store locked up. Store in a well-ventilated place. Keep container tightly closed. |
| Disposal | Dispose of contents and container in accordance with federal, state and local regulations (see Section 13). |
| Hazards not otherwise classified | None identified. Note: ammonia vapor released from the solution is flammable in air between 15% and 28% by volume (see Sections 5 and 10). |
| Hazards classified under 1910.1200(d)(1)(ii) (reaction products) | None identified for the recommended use. Mixing with bleach or other chlorine products forms toxic chloramine gases. |
| Ingredients of unknown acute toxicity | None. |
SECTION 3Composition/information on ingredients
Substance (aqueous solution).
| Chemical name | Common name and synonyms | CAS No. | Concentration (wt %) |
|---|---|---|---|
| Ammonia | Ammonia (present in water as ammonium hydroxide, CAS 1336-21-6) | 7664-41-7 | 25 |
| Water | Water | 7732-18-5 | 75 |
Impurities and stabilizing additives: none that are classified or contribute to the classification.
SECTION 4First-aid measures
| Inhalation | Move the person to fresh air at once. If breathing is difficult, trained personnel give oxygen. If not breathing, give rescue breathing. Get medical attention immediately. Symptoms of lung injury can be delayed up to several hours. |
| Skin contact | Flush skin immediately with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Use the safety shower. Get medical attention immediately. |
| Eye contact | Flush immediately with water for at least 15 minutes, holding eyelids open. Remove contact lenses if easy to do. Continue rinsing on the way to medical care. Get medical attention immediately. |
| Ingestion | Rinse mouth. Do NOT induce vomiting. If the person is conscious, give a small amount of water. Get medical attention immediately. |
| Most important symptoms and effects, acute and delayed | Irritation and burns of eyes, skin, nose and throat; coughing, breathing difficulty, wheezing, chest pain. Delayed pulmonary edema (pink frothy sputum). Eye contact can cause permanent eye injury and blindness. |
| Immediate medical attention and special treatment | Immediate medical attention is required for any eye contact, significant skin contact, ingestion, or inhalation with symptoms. Observe for delayed pulmonary edema after inhalation exposure. |
SECTION 5Fire-fighting measures
| Suitable extinguishing media | The solution does not burn. Use media suitable for the surrounding fire. Water spray or fog absorbs ammonia vapor and cools containers. |
| Unsuitable extinguishing media | Do not put water directly into a leaking container. |
| Specific hazards | Heat drives ammonia gas out of solution. Ammonia vapor is flammable between 15% and 28% in air and can ignite in confined spaces. Closed containers can build pressure when heated. Combustion of ammonia forms nitrogen oxides. |
| Special protective equipment and precautions for fire-fighters | Positive-pressure SCBA and chemical protective clothing. Contain fire-control water; runoff is corrosive and toxic to aquatic life. |
SECTION 6Accidental release measures
| Personal precautions, protective equipment and emergency procedures | Evacuate and isolate the area; keep people upwind. Only trained responders in appropriate PPE (SCBA and chemical protective clothing for large releases) enter the area. Ventilate. Eliminate ignition sources in enclosed areas. Responders follow the employer's emergency response plan. |
| Methods and materials for containment and cleaning up | Stop the leak if it can be done safely. Dike and contain; keep out of storm drains, sewers and waterways. Water spray can knock down vapors; contain the runoff. Small spills: absorb with inert absorbent, or neutralize cautiously with a dilute acid, and collect for disposal. |
| Release reporting | A release of 1,000 lb or more of this solution (ammonium hydroxide RQ) in 24 hours must be reported to the National Response Center, 1-800-424-8802 (40 CFR 302.6), and to the SERC and LEPC under EPCRA 304. Report any release of free ammonia gas that reaches the ammonia RQ of 100 lb. See Section 15. |
SECTION 7Handling and storage
| Precautions for safe handling | Use with local exhaust ventilation. Open containers slowly to relieve pressure. Avoid breathing vapors. Do not get in eyes, on skin or on clothing. Provide eyewash and safety shower (29 CFR 1910.151(c)). |
| Conditions for safe storage, including incompatibilities | Store in a cool, well-ventilated area in tightly closed containers, out of direct sunlight, in an area without drain or sewer access. Steel is suitable. Do not use copper, brass, zinc or galvanized metal; ammonia corrodes them. Keep away from strong oxidizers, acids, halogens (including bleach), and salts of silver and zinc. |
SECTION 8Exposure controls/personal protection
Occupational exposure limits
| Ingredient (CAS) | OSHA PEL (Table Z-1) | NIOSH REL | ACGIH TLV | NIOSH IDLH |
|---|---|---|---|---|
| Ammonia (7664-41-7) | TWA 50 ppm (35 mg/m³) | TWA 25 ppm (18 mg/m³); STEL 35 ppm (27 mg/m³) | TWA 25 ppm; STEL 35 ppm | 300 ppm |
| Appropriate engineering controls | Local exhaust ventilation or closed transfer systems. Ammonia gas detection in bulk storage and transfer areas. Eyewash and safety shower in the work area. |
| Eye/face protection | Chemical splash goggles and a face shield. |
| Skin protection | Chemical-resistant gloves, apron or suit, and boots. Confirm glove breakthrough time with the glove manufacturer's data. |
| Respiratory protection | Use under a written respiratory protection program meeting 29 CFR 1910.134. NIOSH: up to 250 ppm, chemical cartridge respirator with cartridges for ammonia; up to 300 ppm, full-facepiece respirator or gas mask with ammonia cartridges or canister, or supplied air. Above 300 ppm (IDLH) or unknown concentrations: pressure-demand SCBA with full facepiece. |
SECTION 9Physical and chemical properties
| Physical state | Liquid (aqueous solution) |
| Color | Colorless |
| Odor; odor threshold | Intense, pungent, suffocating odor of ammonia. Odor threshold for ammonia (AIHA): mean detection 17 ppm; reported range 0.04 to 53 ppm. |
| Melting point/freezing point | -58 °C (-72 °F) (25% solution) |
| Boiling point | 38 °C (100 °F) (25% solution; ammonia is released on heating) |
| Flammability | Solution is not flammable. Ammonia vapor is flammable in air. |
| Lower/upper flammability limit | Ammonia gas: LEL 15%; UEL 28% |
| Flash point | Not applicable (aqueous solution) |
| Auto-ignition temperature | Ammonia gas: 651 °C (1,204 °F) |
| Decomposition temperature | No data available |
| pH | Strongly alkaline. 1.0 N ammonia solution: pH 11.6. No data available for the 25% solution. |
| Kinematic viscosity | No data available |
| Solubility | Miscible with water |
| Partition coefficient n-octanol/water (log Kow) | No data available |
| Vapor pressure; evaporation rate | 48 kPa (about 360 mmHg) at 20 °C (25% solution); evaporation rate no data available |
| Density/relative density | 0.907 g/mL at 20 °C (about 7.57 lb/gal); relative density about 0.9 |
| Relative vapor density | 0.6 (ammonia gas, air = 1). Ammonia vapor rises, but cold vapor from a large release can stay low. |
| Particle characteristics | Not applicable (liquid) |
SECTION 10Stability and reactivity
| Reactivity | Reacts with acids (exothermic). Corrodes copper, zinc and galvanized surfaces. |
| Chemical stability | Stable in closed containers. Loses ammonia gas when warmed or left open. |
| Possibility of hazardous reactions | Reacts with bleach (sodium hypochlorite) and other chlorine or halogen compounds to form toxic chloramines. Can form explosive compounds with silver and zinc salts and with halogens. |
| Conditions to avoid | Heat, direct sunlight, open containers, confined spaces where vapor can build up. |
| Incompatible materials | Strong oxidizers, acids, halogens, salts of silver and zinc, copper and copper alloys, zinc, galvanized metal. |
| Hazardous decomposition products | Ammonia gas. Nitrogen oxides if ammonia burns. |
SECTION 11Toxicological information
| Likely routes of exposure | Inhalation (ammonia vapor), ingestion, skin and eye contact. |
| Symptoms | Irritation of eyes, nose and throat; breathing difficulty, wheezing, chest pain; pulmonary edema, pink frothy sputum; skin burns and blistering. |
| Target organs | Eyes, skin, respiratory system. |
| Acute toxicity (numerical measures) | Oral LD50 (rat), ammonium hydroxide: 350 mg/kg (Category 4) Inhalation, ammonia gas: LC50 (rat) 16,000 ppm, 15 minutes; LCLo (human) 5,000 ppm Dermal: no data available; corrosive to skin |
| Skin corrosion/irritation | Category 1B. Causes severe skin burns. The vapor is corrosive to the respiratory tract. |
| Serious eye damage/irritation | Category 1. Splashes cause corneal opacity and permanent eye injury. |
| Respiratory or skin sensitization | Not classified. |
| Germ cell mutagenicity; reproductive toxicity | Not classified. |
| Specific target organ toxicity, single exposure | Respiratory effects are communicated as corrosivity to the respiratory tract (Section 2). |
| Specific target organ toxicity, repeated exposure; aspiration | Not classified. |
| Delayed, immediate and chronic effects | Immediate: burns of eyes, skin and airways. Delayed: pulmonary edema can appear hours after inhalation. Chronic: no information available. |
| Interactive effects | No information available. |
| Carcinogenicity | Not listed by NTP (Report on Carcinogens), IARC or OSHA. |
SECTION 12Ecological information
| Ecotoxicity | Very toxic to aquatic life. Ammonium hydroxide LC50, bluegill (Lepomis macrochirus): 0.024 to 0.093 mg/L, 48 hours. Channel catfish LC50: 0.97 to 1.41 mg/L, one week. |
| Persistence and degradability | Ammonia is converted by nitrification in soil and water. |
| Bioaccumulative potential | Not expected to bioaccumulate. |
| Mobility in soil | Mobile in solution; ammonium ion binds to soil. |
| Other adverse effects | Raises the pH of receiving water. |
SECTION 13Disposal considerations
Discarded unused product must be evaluated for the corrosivity characteristic, D002 (aqueous waste with pH 12.5 or higher by Method 9040C, 40 CFR 261.22). Ammonium hydroxide is not a listed P or U waste. Do not discharge to sewers or storm drains. Manage under 40 CFR Parts 260 through 273 and state rules. Empty containers retain ammonia vapor; keep closed and manage under 40 CFR 261.7.
SECTION 14Transport information
| UN number | UN2672 |
| UN proper shipping name | Ammonia solution, relative density between 0.880 and 0.957 at 15 degrees C in water, with more than 10 percent but not more than 35 percent ammonia |
| Transport hazard class | 8 |
| Packing group | III |
| Basic description (49 CFR 172.202) | UN2672, Ammonia solution, relative density between 0.880 and 0.957 at 15 degrees C in water, with more than 10 percent but not more than 35 percent ammonia, 8, III. Add "RQ" when one package contains 1,000 lb or more of the solution (49 CFR 172.203(c)). The RQ is applied to the solution as ammonium hydroxide, following EPA's guidance "Determining the Amount Released for Ammonia and Ammonium Hydroxide for Release Notification Requirements under CERCLA Section 103 and EPCRA Section 304" (epa.gov/epcra). |
| Environmental hazards | Hazardous substance: ammonium hydroxide, RQ 1,000 lb (454 kg) per 40 CFR 302.4. Marine pollutant: Yes, listed in Appendix B to 49 CFR 172.101 (not a severe marine pollutant). Except when any part of the trip is by vessel, the marine pollutant requirements do not apply to non-bulk packagings transported by motor vehicle, rail car or aircraft (49 CFR 171.4(c)(1)). |
| Transport in bulk (IMO instruments) | No information available. |
| Special precautions | Emergency Response Guidebook Guide 154. Special provisions 336, IB3, IP8, T7, TP2. Packaging: 49 CFR 173.154 (exceptions), 173.203 (non-bulk), 173.241 (bulk). Vessel stowage A, codes 40, 52, 85. |
SECTION 15Regulatory information
| TSCA | Ammonium hydroxide and ammonia: listed on the TSCA Inventory (active). |
| CERCLA (40 CFR 302.4) | Ammonium hydroxide (1336-21-6): RQ 1,000 lb (454 kg). Ammonia (7664-41-7): RQ 100 lb (45.4 kg). EPA guidance: a release of the solution is reported against the ammonium hydroxide RQ without applying the mixture rule to the ammonia; free ammonia released from the tank headspace is reported against the ammonia RQ. Basis: EPA, "Determining the Amount Released for Ammonia and Ammonium Hydroxide for Release Notification Requirements under CERCLA Section 103 and EPCRA Section 304" (epa.gov/epcra). |
| Clean Water Act 311 (40 CFR 116.4) | Ammonia (7664-41-7) and ammonium hydroxide (1336-21-6) are designated hazardous substances under section 311 of the Clean Water Act; the designation includes solutions (40 CFR 116.4; Table 302.4, statutory code 1). RQ: ammonium hydroxide 1,000 lb (454 kg); ammonia 100 lb (45.4 kg). |
| EPCRA 302/304 (40 CFR 355, Appendix A) | Ammonia is an extremely hazardous substance: TPQ 500 lb; RQ 100 lb. The quantity of ammonia in a mixture is weight percent times mixture weight (40 CFR 355.13). |
| EPCRA 311/312 (40 CFR 370) | Hazardous chemical under the OSHA HCS. For an EHS the threshold is 500 lb or the TPQ, whichever is lower (40 CFR 370.10(a)(1)). |
| EPCRA 313 (40 CFR 372.65) | Ammonia is listed; under the listing qualifier, 10% of total aqueous ammonia is reportable. EPA's TRI guidance for ammonia applies the 1% de minimis to the total aqueous ammonia concentration; this product is 25%, so supplier notification applies (40 CFR 372.45). Supplier notification: This product contains a toxic chemical subject to the reporting requirements of section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 and 40 CFR Part 372: Ammonia, CAS 7664-41-7, 25% by weight (total aqueous ammonia; 10% of total aqueous ammonia is reportable under the 40 CFR 372.65 listing). This notice must not be detached from this SDS. Any copying and redistribution of this SDS must include this notice. |
| Clean Air Act 112(r) (40 CFR 68.130) | Listed: "Ammonia (conc 20% or greater)," CAS 7664-41-7, threshold quantity 20,000 lb (Table 1 to 40 CFR 68.130). The mixture exemptions in 40 CFR 68.115(b)(1) (below 1%, or partial pressure below 10 mmHg) do not apply to a 25% solution. |
| OSHA Process Safety Management (29 CFR 1910.119) | Not covered as supplied. Appendix A lists ammonia solutions only above 44% ammonia by weight (threshold 15,000 lb). |
SECTION 16Other information, including date of preparation or last revision
| Date of preparation or last revision | August 18, 2025. Version 2.4. Supersedes June 2, 2023. |
| Revision note | Updated to the Hazard Communication Standard as amended May 20, 2024 (89 FR 44144) and corrected October 9, 2024 (89 FR 81829). Added corrosivity to the respiratory tract. |
| Abbreviations | EHS: extremely hazardous substance. IDLH: immediately dangerous to life or health. LCLo: lowest published lethal concentration. LEPC: Local Emergency Planning Committee. RQ: reportable quantity. SERC: State Emergency Response Commission. TPQ: threshold planning quantity. |